Arun K. Ghosh,Sandra Gemma's Structure-based Design of Drugs and Other Bioactive PDF

By Arun K. Ghosh,Sandra Gemma

ISBN-10: 3527333657

ISBN-13: 9783527333653

Drug layout is a posh, tough and leading edge learn region. Structure-based molecular layout has remodeled the drug discovery method in sleek drugs. characteristically, concentration has been put on computational, structural or man made equipment merely in isolation. This one-of-akind advisor integrates all 3 ability units for a whole photograph of up to date structure-based design.

This functional strategy offers the instruments to advance a high-affinity ligand with drug-like homes for a given drug objective for which a high-resolution constitution exists. The authors use a number of examples of lately built medications to give "best perform" tools in structurebased drug layout with either beginners and training researchers in brain. in terms of a gently balanced mixture of theoretical heritage and case stories from medicinal chemistry functions, readers will quick and successfully grasp the fundamental talents of profitable drug design.

This booklet is geared toward new and lively medicinal chemists, biochemists, pharmacologists, usual product chemists and people operating in drug discovery within the pharmaceutical undefined. it really is hugely suggested as a table connection with advisor scholars in medicinal and chemical sciences in addition to to help researchers engaged in drug layout today.

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Structure-based Design of Drugs and Other Bioactive Molecules: Tools and Strategies by Arun K. Ghosh,Sandra Gemma

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